B0770

Brillantblau G

≥80% purity (HPLC), powder

• Synonym(e): Acid Blue 90, Coomassie Brillantblau G 250
• Empirische Formel (Hill-System): C₄₇H₄₈N₃NaO₇S₂
• CAS-Nummer: 6104-58-1
• Molekulargewicht: 854.02
• Farbindexnummer: 42655
• Beilstein: 5230822
• EG-Nummer: 228-058-4
• MDL-Nummer: MFCD00078482
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24891535
• NACRES: NA.47

Eigenschaften

• product name: Brillantblau G, pure
• Qualitätsniveau: 200
• Assay: ≥80.0% (HPLC)
• Form: powder
• Farbe: dark violet
• Löslichkeit: H₂O: 1 mg/mL
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: [Na+].CCOc1ccc(Nc2ccc(cc2)C(\c3ccc(cc3C)N(CC)Cc4cccc(c4)S([O-])(=O)=O)=C5\C=CC(\C=C5C)=[N+](\CC)Cc6cccc(c6)S([O-])(=O)=O)cc1
• InChI: 1S/C47H49N3O7S2.Na/c1-6-49(31-35-11-9-13-43(29-35)58(51,52)53)40-21-25-45(33(4)27-40)47(37-15-17-38(18-16-37)48-39-19-23-42(24-20-39)57-8-3)46-26-22-41(28-34(46)5)50(7-2)32-36-12-10-14-44(30-36)59(54,55)56;/h9-30H,6-8,31-32H2,1-5H3,(H2,51,52,53,54,55,56);/q;+1/p-1
• InChIKey: RWVGQQGBQSJDQV-UHFFFAOYSA-M

Beschreibung

Anwendung

Brilliant Blue G has been used for determining the urine protein concentration. It has been used for the protein band detection after SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). It has been used as a P2X7R (purinergic receptor) antagonist.

Biochem./physiol. Wirkung

P2X₇-Rezeptor-Agonist

Brilliant Blue G is used for staining protein(s) in polyacrylamide gels. It is also a P2X7 purinergic receptor antagonist. The receptor is mainly involved in neuroinflammatory events. In human SOD1G93A amyotrophic lateral sclerosis mouse, administration of brilliant blue G reduces body weight loss. However, it does not affect survival or motor coordination in transgenic mice.

Rechtliche Hinweise

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)