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Merck

AB5372

Sigma-Aldrich

Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB

serum, Chemicon®

Synonym(e):

BDNF/NT-3 Growth Factors Receptor, Tyrosine Kinase Receptor B

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

rat, human

Hersteller/Markenname

Chemicon®

Methode(n)

immunohistochemistry: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... NTRK2(4915)

Spezifität

TrkB. The sequence used for the immunogen was chosen to avoid cross reactivity with trkA or trkC.

Immunogen

A synthetic peptide from rat trkB
Epitope: a.a. 54-67 rtrkB

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurochemie & Neurotrophine
Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB detects level of Trk B & has been published & validated for use in IH & WB.
Immunohistochemistry: 1:2,000-1:3,000. The antibody reacts well with tissue from the rat spinal cord.
Immunoblotting: 1:1,000-1:1,500 on rat membrane preparations. The antibody should be
evaluated for use in Western blot by the end user. Its utility will be dependant on the level of
the protein expressed in the tissues or cells being tested.
Optimal working dilutions must be determined by end user.

Physikalische Form

Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.

Lagerung und Haltbarkeit

Maintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Zitao Zhang et al.
Molecular medicine reports, 15(3), 1362-1367 (2017-01-19)
Brain‑derived neurotrophic factor (BDNF), a member of the neurotropic family, is expressed in osteoblast‑like cells of a fracture callus, however, its role in fracture healing remains to be fully elucidated. Osteoblasts isolated from Sprague Dawley rats were stimulated by BDNF
Amy A Robinson et al.
GeroScience, 40(1), 31-47 (2018-01-23)
Mammalian aging is associated with decline in cognitive functions. Studies searching for a cause of cognitive aging initially focused on neuronal loss but quantitative investigations of rat, monkey, and human brain using stereology demonstrated that in normal aging, unlike in
Laurens W J Bosman et al.
Brain cell biology, 35(1), 87-101 (2007-10-18)
The receptor tyrosine kinase TrkB and its ligands, brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5), are critically important for growth, survival and activity-dependent synaptic strengthening in the central nervous system. These TrkB-mediated actions occur in a highly cell-type specific manner.
Rita Machaalani et al.
Neurotoxicology, 74, 40-46 (2019-05-24)
Cigarette smoke exposure during pregnancy into infancy affects brain growth and development in both short and long term (into adulthood). Using a mouse model of pre- into post- natal cigarette smoke exposure (SE), we aimed to determine the effects on
Ji Min Yu et al.
Methods in molecular biology (Clifton, N.J.), 702, 219-231 (2010-11-18)
While adult stem cells can be induced to transdifferentiate into multiple lineages of cells or tissues, their plasticity and utility for human therapy remains controversial. In this chapter, we describe methods for the transdifferentiation of human adipose tissue-derived stem cells

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