700055P

5α,6β-dihydroxycholestanol-d7

Avanti Research^™ - A Croda Brand

• Synonym(e): 3β,5α,6β-trihydroxycholestane (d7)
• Empirische Formel (Hill-System): C₂₇H₄₁D₇O₃
• CAS-Nummer: 127684-07-5
• Molekulargewicht: 427.71
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Beschreibung: cholestane-3β,5α,6β-triol-d7
• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (700055P-1mg); pkg of 1 × 5 mg (700055P-5mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@@]3(O)[C@H](O)C2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

Beschreibung

Allgemeine Beschreibung

5α,6β-dihydroxycholestanol is a structural derivative of cholesterol and is an abundant oxysterols. 5α,6β-dihydroxycholestanol-d7 is a deuterated form of 5α,6β-dihydroxycholestanol.

Anwendung

5α,6β-dihydroxycholestanol-d7 has been used as an analyte in liquid chromatography with tandem mass spectrometry (LC-MS-MS) analysis based multiple reaction monitoring (MRM) studies and as an internal standard in tandem mass spectrometry (MS/MS) for analysis of plasma samples.

Biochem./physiol. Wirkung

5α,6β-dihydroxycholestanol (5α,6β-diOH-Chol) or cholestane-3β,5α,6β-triol (C-triol) levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection. It has ,neuroprotective functionality and may elicit protection against neuronal injury during ischemia.

Verpackung

5 mL Amber Glass Screw Cap Vial (700055P-1mg)

5 mL Amber Glass Screw Cap Vial (700055P-5mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available