900760

Sodium 5-(trifluoromethyl)pyridine-2-sulfinate

≥95%

• Synonym(e): Willis 5-trifluoromethyl pyridine 2-sulfinate
• Empirische Formel (Hill-System): C₆H₃F₃NNaO₂S
• Molekulargewicht: 233.14
• UNSPSC-Code: 12352200
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• Form: powder
• Eignung der Reaktion: reaction type: C-C Bond Formation
• mp (Schmelzpunkt): 340 °C (dec)

Beschreibung

Anwendung

This 2-pyridylsulfinate enables Suzuki-Miyaura cross coupling with aryl halides to access diverse pyridine derivatives as reported by the laboratory of Michael Willis.. No longer impeded by unstable 2-pyridyl boronates, the sulfinate alternatives provide Pd-catalyzed coupling routes to therapeutically valuable pyridine rings.

Sonstige Hinweise

• Technology Spotlight: Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions.
• Pyridine Sulfinates as General Nucleophilic Coupling Partners in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable