381551

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-on

97%

• Synonym(e): (Ipriflavon)
• Empirische Formel (Hill-System): C₁₈H₁₆O₃
• CAS-Nummer: 35212-22-7
• Molekulargewicht: 280.32
• MDL-Nummer: MFCD00221719
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24863826
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• mp (Schmelzpunkt): 116-120 °C (lit.)
• SMILES String: CC(C)Oc1ccc2c(OC=C(C2=O)c3ccccc3)c1
• InChI: 1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
• InChIKey: SFBODOKJTYAUCM-UHFFFAOYSA-N
• Angaben zum Gen: rat ... Alpl(25586)

Beschreibung

Allgemeine Beschreibung

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.

Anwendung

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)