XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Synonyme:
KARP-1, KARP1, KU80, KUB2, Ku86, NFIV
Spezies:
Human XRCC5 (7520), Mouse Xrcc5 (22596), Rat Xrcc5 (363247), Horse XRCC5 (100055031), dog XRCC5 (478902), chicken XRCC5 (424222), Zebrafish xrcc5 (449848), domestic guinea pig Xrcc5 (100728001), naked mole-rat Xrcc5 (101719341), sheep XRCC5 (101107255) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(7520) Summary: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
- Mouse(22596) X-ray repair complementing defective repair in Chinese hamster cells 5
- Rat(363247) X-ray repair complementing defective repair in Chinese hamster cells 5
- Horse(100055031) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- dog(478902) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- chicken(424222) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- Zebrafish(449848) X-ray repair complementing defective repair in Chinese hamster cells 5
- domestic guinea pig(100728001) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- naked mole-rat(101719341) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- sheep(101107255) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- Domestic Rabbit(100347656) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- domestic cat(101083534) X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-XRCC5/Ku80 Antibody, clone 1C9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey
Anwendung
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-Ku80 (pThr714) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-XRCC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-XRCC5 antibody produced in mouse, clone 3D8, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-KU80 antibody, Rabbit monoclonal, clone SP130, recombinant, expressed in proprietary host, affinity isolated antibody,
Speziesreaktivität
bovine, human, mouse, rat
Anwendung
immunohistochemistry
western blot
western blot