PTPRJ
protein tyrosine phosphatase, receptor type, J
Synonyme:
CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1
Spezies:
Human PTPRJ (5795), Mouse Ptprj (19271), Rat Ptprj (29645), chicken PTPRJ (395330), Domestic Rabbit PTPRJ (100347798), domestic cat PTPRJ (101086598), dog PTPRJ (483617), Horse PTPRJ (100058689), cow PTPRJ (508150), sheep PTPRJ (101121292) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(5795) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19271) protein tyrosine phosphatase, receptor type, J
- Rat(29645) protein tyrosine phosphatase, receptor type, J
- chicken(395330) protein tyrosine phosphatase, receptor type, J
- Domestic Rabbit(100347798) protein tyrosine phosphatase, receptor type, J
- domestic cat(101086598) protein tyrosine phosphatase, receptor type, J
- dog(483617) protein tyrosine phosphatase, receptor type, J
- Horse(100058689) protein tyrosine phosphatase, receptor type, J
- cow(508150) protein tyrosine phosphatase, receptor type, J
- sheep(101121292) protein tyrosine phosphatase, receptor type, J
- domestic guinea pig(100729887) protein tyrosine phosphatase, receptor type, J
- naked mole-rat(101726039) protein tyrosine phosphatase, receptor type, J
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Produktnummer
Beschreibung
Spezies
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-CD148-APC antibody produced in mouse, clone MEM-CD148/05,
Speziesreaktivität
Anwendung
flow cytometry
Anti-Protein-Tyrosinphosphatase eta (CD148) Antikörper, Klon 8A-1, clone 8A-1, from hamster(Syrian),
Speziesreaktivität
mouse
Anwendung
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PTPRJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Monoclonal Anti-CD148 antibody produced in mouse, clone MEM-CD148/05, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
flow cytometry
Anti-CD148/DEP-1-Antikörper, Klon Ab1 (azidfrei), clone Ab 1, from mouse,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
immunoprecipitation (IP)
inhibition assay
western blot
immunoprecipitation (IP)
inhibition assay
western blot
Proteins
Produktnummer
Beschreibung
Spezies