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PRG2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

Synonyme:
BMPG, MBP, MBP1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5553) Summary: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(19074) proteoglycan 2, bone marrow
  • Rat(58826) proteoglycan 2, bone marrow
  • Horse(100062803) proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Eosinophil-Major-Basic-Protein-Antikörper, Klon BMK13, clone BMK13, Chemicon®, from mouse,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry

western blot
Anti-PRG2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PRG2,
Spezies
human