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POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

Synonyme:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
  • Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
  • Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
  • cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
  • sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-RNA-Polymerase II Antikörper, CTD-Antikörper, Klon 8WG16, clone 8WG16, from mouse,
Speziesreaktivität
human, yeast
Anwendung
dot blot
immunoprecipitation (IP)

inhibition assay

western blot
Anti-Phospho-RNA-Pol-II-(Ser5-)Antikörper, Klon 1H4B6, clone 1H4B6, from rat,
Speziesreaktivität
canine, human, monkey, mouse, rat
Anwendung
ChIP
ELISA

immunocytochemistry

western blot
Monoclonal Anti-phospho-RNA polymerase II CTD (pSer2) antibody produced in rat, clone 3E7C7, purified from hybridoma cell culture,
Speziesreaktivität
Anwendung
flow cytometry
immunofluorescence

western blot
Anti-phospho-RNA-Pol-II(Ser2)-Antikörper, Klon 3E7C7, clone 3E7C7, from rat,
Speziesreaktivität
canine, human, monkey, mouse, rat
Anwendung
ChIP
ELISA

immunocytochemistry

western blot
Anti-POLR2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence

Proteins

Produktnummer
Beschreibung
Spezies
RNA Polymerase II, C-terminal domain, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Spezies
human
RNA Polymerase II, C-terminal human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human POLR2A,
Spezies
human
MISSION® esiRNA, targeting mouse Polr2a,
Spezies
mouse