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Merck

PIAS2

protein inhibitor of activated STAT, 2

Synonyme:
ARIP3, DIP, MIZ, MIZ1, PIASX, PIASX-ALPHA, PIASX-BETA, SIZ2, ZMIZ4
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(9063) Summary: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]
  • Mouse(17344) protein inhibitor of activated STAT 2
  • Rat(83422) protein inhibitor of activated STAT, 2
  • Zebrafish(564149) protein inhibitor of activated STAT, 2
  • domestic guinea pig(100718605) protein inhibitor of activated STAT, 2
  • naked mole-rat(101709303) protein inhibitor of activated STAT, 2
  • sheep(101112782) protein inhibitor of activated STAT, 2
  • cow(533403) protein inhibitor of activated STAT, 2
  • Horse(100068879) protein inhibitor of activated STAT, 2
  • domestic cat(101081835) protein inhibitor of activated STAT, 2
  • dog(480147) protein inhibitor of activated STAT, 2
  • chicken(416383) protein inhibitor of activated STAT, 2

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Pias2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
Monoclonal Anti-PIAS2 antibody produced in mouse, clone 1F7, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-PIAS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-PIAS2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
Anti-PIAS2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
dog, horse, human, mouse, rabbit
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PIAS2,
Spezies
human
MISSION® esiRNA, targeting mouse Pias2,
Spezies
mouse