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PARN

poly(A)-specific ribonuclease

Synonyme:
DAN
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5073) Summary: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(74108) poly(A)-specific ribonuclease (deadenylation nuclease)
  • Rat(360464) poly(A)-specific ribonuclease
  • domestic guinea pig(100732149) poly(A)-specific ribonuclease
  • naked mole-rat(101715275) poly(A)-specific ribonuclease
  • cow(524155) poly(A)-specific ribonuclease
  • Zebrafish(791461) poly(A)-specific ribonuclease (deadenylation nuclease)
  • Domestic Rabbit(100351489) poly(A)-specific ribonuclease
  • domestic cat(101100021) poly(A)-specific ribonuclease
  • dog(479839) poly(A)-specific ribonuclease
  • chicken(416423) poly(A)-specific ribonuclease
  • sheep(101112185) poly(A)-specific ribonuclease

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ELISA

Produktnummer
Beschreibung
Spezies
Mouse Parn / Poly(A)-specific Ribonuclease PARN ELISA Kit, for serum, plasma and cell culture supernatants,
Spezies
mouse

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PARN antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-PARN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
western blot
Anti-PARN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-PARN antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human PARN,
Spezies
human
MISSION® esiRNA, targeting mouse Parn,
Spezies
mouse