PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Synonyme:
AR-JP, LPRS2, PDJ, PRKN
Spezies:
Human PARK2 (5071), Mouse Park2 (50873), Rat Park2 (56816), cow PARK2 (530858), naked mole-rat Park2 (101700770), domestic guinea pig Park2 (100724550), Horse PARK2 (100057832), Zebrafish park2 (550328), chicken PARK2 (421577), dog PARK2 (612316) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(5071) Summary: The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
- Mouse(50873) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- Rat(56816) parkinson protein 2, E3 ubiquitin protein ligase
- cow(530858) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- naked mole-rat(101700770) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic guinea pig(100724550) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Horse(100057832) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Zebrafish(550328) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- chicken(421577) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- dog(612316) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic cat(101098228) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- sheep(101113503) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Parkin Antibody, clone PRK8, ascites fluid, clone PRK8, Upstate®,
Speziesreaktivität
human, mouse
Anwendung
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-PARK2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
canine, human, mouse, rat
Anwendung
ELISA
western blot
western blot
ANTI-PARKIN(C-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
flow cytometry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Parkin antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Parkin Antibody, a.a. 305-323, serum, Chemicon®,
Speziesreaktivität
human, rat
Anwendung
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Produktnummer
Beschreibung
Spezies