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IDH3B

isocitrate dehydrogenase 3 (NAD+) beta

Synonyme:
H-IDHB, RP46
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3420) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(170718) isocitrate dehydrogenase 3 (NAD+) beta
  • Rat(94173) isocitrate dehydrogenase 3 (NAD+) beta
  • domestic guinea pig(100717400) isocitrate dehydrogenase 3 (NAD+) beta
  • Zebrafish(415247) isocitrate dehydrogenase 3 (NAD+) beta
  • dog(477177) isocitrate dehydrogenase 3 (NAD+) beta
  • cow(613338) isocitrate dehydrogenase 3 (NAD+) beta
  • domestic cat(101099035) isocitrate dehydrogenase 3 (NAD+) beta
  • chicken(426573) isocitrate dehydrogenase 3 (NAD+) beta
  • naked mole-rat(101709094) isocitrate dehydrogenase 3 (NAD+) beta
  • sheep(101104080) isocitrate dehydrogenase 3 (NAD+) beta

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-IDH3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-IDH3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
Anti-IDH3B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Monoclonal Anti-IDH3B antibody produced in mouse, clone 3A10, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA

Kits

Produktnummer
Beschreibung
Spezies
IDH-Aktivitätassay-Kit, sufficient for 100 colorimetric tests,
Spezies
mouse, rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Idh3b,
Spezies
mouse