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Merck

HRH3

histamine receptor H3

Synonyme:
GPCR97, HH3R
Spezies:
Human HRH3 (11255), Mouse Hrh3 (99296), Rat Hrh3 (85268), sheep HRH3 (101121700), Domestic Rabbit HRH3 (100009035), chicken HRH3 (428147), dog HRH3 (477282), domestic cat HRH3 (101084437), cow HRH3 (789851), Zebrafish hrh3 (561773)
UniProtKB-ID:
Q9Y5N1, Q4QRI7, Q9GZX2, Q9H4K8
Gen-ID:
  • Human(11255) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
  • Mouse(99296) histamine receptor H3
  • Rat(85268) histamine receptor H3
  • sheep(101121700) histamine receptor H3
  • Domestic Rabbit(100009035) histamine receptor H3
  • chicken(428147) histamine receptor H3
  • dog(477282) histamine receptor H3
  • domestic cat(101084437) histamine receptor H3
  • cow(789851) histamine receptor H3
  • Zebrafish(561773) histamine receptor H3
  • domestic guinea pig(100135541) histamine receptor H3

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
H128
(R)(−)-α-Methylhistamine dihydrochloride, solid, ≥98% (HPLC),
Spezies
human
I135
Imetit dihydrobromide, ≥98% (HPLC),
Spezies
human
B4638
Betahistin -dihydrochlorid, ≥98%,
Spezies
human
PHR2097
Betahistin-Hydrochlorid, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Y0000391
Betahistin -dihydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
T123
Thioperamide maleate salt, solid,
Spezies
human
B4638
Betahistin -dihydrochlorid, ≥98%,
Spezies
human
PHR2097
Betahistin-Hydrochlorid, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Y0000391
Betahistin -dihydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
M28804
2-(2-Methylaminoethyl)pyridin, 97%,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB5701457
Anti-HRH3 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
H7125
Histamin, ≥97.0%,
Spezies
human, rat

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
M4910
1-Methylhistamin -dihydrochlorid, ≥98% (TLC), powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU141391
MISSION® esiRNA, targeting human HRH3,
Spezies
human