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Merck

HLA-DMA

major histocompatibility complex, class II, DM alpha

Synonyme:
D6S222E, DMA, HLADM, RING6
Spezies:
Human HLA-DMA (3108)
UniProtKB-ID:
P28067, Q29639, Q29640
Gen-ID:
  • Human(3108) Summary: HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
HPA017295
Anti-HLA-DMA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
HPA012750
Anti-HLA-DMA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
WH0003108M1
Monoclonal Anti-HLA-DMA antibody produced in mouse, clone 3F12-F11, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry
western blot
SAB1408586
Anti-HLA-DMA antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
western blot