GRN
granulin
Synonyme:
CLN11, GEP, GP88, PCDGF, PEPI, PGRN
Spezies:
Human GRN (2896), Mouse Grn (14824), Rat Grn (29143), fruit fly grn (40962), dog GRN (480501), Horse GRN (100051035), domestic cat GRN (101100680), cow GRN (767942), sheep GRN (101115470), Domestic Rabbit GRN (100349528) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(2896) Summary: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
- Mouse(14824) granulin
- Rat(29143) granulin
- fruit fly(40962) grain
- dog(480501) granulin
- Horse(100051035) granulin
- domestic cat(101100680) granulin
- cow(767942) granulin
- sheep(101115470) granulin
- Domestic Rabbit(100349528) granulin
- domestic guinea pig(100135533) granulin
- naked mole-rat(101715753) granulin
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ELISA
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Granulin (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
western blot
Anti-GRN antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-Progranulin/GRN-Antikörper, Klon 8H10, clone 8H10, from rat,
Speziesreaktivität
mouse
Anwendung
immunohistochemistry
western blot
western blot
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry
Proteins
Produktnummer
Beschreibung
Spezies
Progranulin human, recombinant, expressed in HEK 293 cells, untagged, >95% (SDS-PAGE),
Spezies
human
Progranulin mouse, recombinant, expressed in HEK 293 cells, untagged, >95% (SDS-PAGE),
Spezies
mouse
Granulin C human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Spezies
human
Progranulin mouse, recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE),
Spezies
mouse
Progranulin rat, recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE),
Spezies
rat