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GP1BA

glycoprotein Ib (platelet), alpha polypeptide

Synonyme:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
  • Mouse(14723) glycoprotein 1b, alpha polypeptide
  • Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
  • chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
  • naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
  • domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
  • sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
  • cow(504977) glycoprotein Ib (platelet), alpha polypeptide
  • domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
  • dog(403638) glycoprotein Ib (platelet), alpha polypeptide

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ELISA

Produktnummer
Beschreibung
Spezies
Human CD42b ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CD42B antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP219, affinity isolated antibody,
Speziesreaktivität
dog, human, mouse
Anwendung
flow cytometry
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, nonhuman primates
Anwendung
flow cytometry
Anti-GP1BA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone AK2,
Speziesreaktivität
human
Anwendung
flow cytometry
Monoclonal Anti-GP1BA antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Gp1ba,
Spezies
mouse
MISSION® esiRNA, targeting human GP1BA,
Spezies
human