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GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

Synonyme:
CAE2, ECA2, GEFSP3
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2566) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14406) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  • Rat(29709) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Horse(100059571) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • sheep(101118526) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Zebrafish(553402) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • chicken(396289) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • dog(489141) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic cat(100286791) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • cow(282240) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic guinea pig(100723005) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • naked mole-rat(101718598) gamma-aminobutyric acid (GABA) A receptor, gamma 2

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Oxazepam, ,
Spezies
human
Meprobamat, analytical standard,
Spezies
human
4-Aminobutansäure, ≥99%,
Spezies
human, rat
2-Brom-2-chlor-1,1,1-trifluorethan, ≥99%,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Zolpidem, ≥98% (HPLC), solid,
Spezies
human, rat
Midazolam -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Diazepam -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Oxazepam -Lösung, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Etiocholan-3α-ol-17-on, ,
Spezies
human, rat
Zolpidem, ≥98% (HPLC), solid,
Spezies
human, rat
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Flunitrazepam, ,
Spezies
human
Clonazepam, powder,
Spezies
human, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop, Chemicon®, from rabbit,
Speziesreaktivität
rat
Anwendung
immunoprecipitation (IP)
western blot
Anti-GABA(A) receptor subunit gamma-2 Antibody, serum, from rabbit,
Speziesreaktivität
human, rat
Anwendung
western blot
Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8, clone 10F10-C1-B8, from mouse,
Speziesreaktivität
rat
Anwendung
immunocytochemistry
western blot
Anti-GABRG2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, human, mouse, rat
Anwendung
ELISA
western blot
Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
bovine, human, mouse, rat
Anwendung
western blot

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
Etiocholan-3α-ol-17-on, ,
Spezies
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Spezies
human, mouse
5α-Pregnan-3α-ol-20-one, solid,
Spezies
human, mouse, rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GABRG2,
Spezies
human