ESR1
estrogen receptor 1
Synonyme:
ER, ESR, ESRA, ESTRR, Era, NR3A1
Spezies:
Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), domestic cat ESR1 (552888), dog ESR1 (403640), chicken ESR1 (396099), Thale Cress ESR1 (837856), Horse ESR1 (791249), Zebrafish esr1 (259252), cow ESR1 (407238) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
- Mouse(13982) estrogen receptor 1 (alpha)
- Rat(24890) estrogen receptor 1
- domestic cat(552888) estrogen receptor 1
- dog(403640) estrogen receptor 1
- chicken(396099) estrogen receptor 1
- Thale Cress(837856) ethylene-responsive transcription factor ESR1
- Horse(791249) estrogen receptor 1
- Zebrafish(259252) estrogen receptor 1
- cow(407238) estrogen receptor 1
- Goat(100860768) estrogen receptor 1
- sheep(443228) estrogen receptor 1
- domestic guinea pig(100713276) estrogen receptor 1
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Small Molecule - Activator
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Spezies
β-Nicotinamidadenin-Dinucleotid Hydrat, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
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human
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17β-Estradiol -Lösung, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
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Spezies
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Small Molecule - Antagonist
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
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Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
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Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
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Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
western blot
western blot
Monoclonal Anti-ESR1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1196, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
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Speziesreaktivität
hamster, human, mouse, rat
Anwendung
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Produktnummer
Beschreibung
Spezies
Small Molecule - Mixed Agonist/Antagonist
Produktnummer
Beschreibung
Spezies
Proteins
Produktnummer
Beschreibung
Spezies
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Spezies
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esiRNA
Produktnummer
Beschreibung
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