Direkt zum Inhalt
Merck

DDR2

discoidin domain receptor tyrosine kinase 2

Synonyme:
MIG20a, NTRKR3, TKT, TYRO10
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4921) Summary: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(18214) discoidin domain receptor family, member 2
  • Rat(685781) discoidin domain receptor tyrosine kinase 2
  • chicken(396404) discoidin domain receptor tyrosine kinase 2
  • dog(478987) discoidin domain receptor tyrosine kinase 2
  • Zebrafish(559428) discoidin domain receptor family, member 2
  • domestic guinea pig(100729537) discoidin domain receptor tyrosine kinase 2
  • sheep(101109754) discoidin domain receptor tyrosine kinase 2
  • naked mole-rat(101712349) discoidin domain receptor tyrosine kinase 2
  • cow(533523) discoidin domain receptor tyrosine kinase 2
  • Horse(100058300) discoidin domain receptor tyrosine kinase 2
  • domestic cat(101085267) discoidin domain receptor tyrosine kinase 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Produktnummer
Beschreibung
Spezies
Phosphotyrosine DDR2 / Discoidin domain-containing Receptor 2 ELISA Kit, ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-DDR2 Antibody, clone 1M8U7, Rabbit Monoclonal, ,
Speziesreaktivität
human, rat
Anwendung
western blot
Monoclonal Anti-DDR2 antibody produced in mouse, clone 3B11E4, ascites fluid,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
MONOCLONAL ANTI-DDR2 antibody produced in mouse, clone 484CT5.5.4, crude ascites, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-DDR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Ddr2,
Spezies
mouse
MISSION® esiRNA, targeting human DDR2,
Spezies
human
MISSION® esiRNA, targeting mouse Ddr2,
Spezies
mouse