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Merck

DDR1

discoidin domain receptor tyrosine kinase 1

Synonyme:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(12305) discoidin domain receptor family, member 1
  • Rat(25678) discoidin domain receptor tyrosine kinase 1
  • Horse(100050861) discoidin domain receptor tyrosine kinase 1
  • naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
  • domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
  • sheep(101104279) discoidin domain receptor tyrosine kinase 1
  • cow(534092) discoidin domain receptor tyrosine kinase 1
  • domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
  • dog(474832) discoidin domain receptor tyrosine kinase 1
  • Zebrafish(100007346) discoidin domain receptor family, member 1

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ELISA

Produktnummer
Beschreibung
Spezies
Human DDR1 ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Anti-CD167a/DDR1 Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, human, monkey, mouse, porcine, rat
Anwendung
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-Phospho-DDR1-Y792 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-CD167a/DDR1-Antikörper, Klon 5D5, clone 5D5, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry
Anti-DDR1 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, dog, horse, human, monkey, pig
Anwendung
immunohistochemistry

Proteins

Produktnummer
Beschreibung
Spezies
DDR1 (444-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Ddr1,
Spezies
mouse
MISSION® esiRNA, targeting human DDR1,
Spezies
human