CYBB
cytochrome b-245, beta polypeptide
Synonyme:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Spezies:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), cow CYBB (281112), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801), dog CYBB (491825), chicken CYBB (418581), Zebrafish cybb (393386)
UniProtKB-ID:
Gen-ID:
- Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
- Mouse(13058) cytochrome b-245, beta polypeptide
- Rat(66021) cytochrome b-245, beta polypeptide
- cow(281112) cytochrome b-245, beta polypeptide
- sheep(100036757) cytochrome b-245, beta polypeptide
- Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
- dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
- chicken(418581) cytochrome b-245, beta polypeptide
- Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CYBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-GP91-PHOX-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
human
Anwendung
western blot
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rabbit, rat
Anwendung
western blot
Anti-gp91phox (NOX2) Antibody, ,
Speziesreaktivität
human
Anwendung
flow cytometry
western blot
western blot
Anti-gp91phox (NOX2) Antibody, ,
Speziesreaktivität
human
Anwendung
flow cytometry
inhibition assay
western blot
inhibition assay
western blot
esiRNA
Produktnummer
Beschreibung
Spezies