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Merck

CSF1R

colony stimulating factor 1 receptor

Synonyme:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(12978) colony stimulating factor 1 receptor
  • Rat(307403) colony stimulating factor 1 receptor
  • domestic guinea pig(100726053) colony stimulating factor 1 receptor
  • naked mole-rat(101719513) colony stimulating factor 1 receptor
  • sheep(101109969) colony stimulating factor 1 receptor
  • cow(509418) colony stimulating factor 1 receptor
  • domestic cat(493706) colony stimulating factor 1 receptor
  • Horse(100060422) colony stimulating factor 1 receptor
  • dog(489188) colony stimulating factor 1 receptor
  • chicken(396406) colony stimulating factor 1 receptor

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ELISA

Produktnummer
Beschreibung
Spezies
Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Spezies
human
Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CSF1R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-CSF1R antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
canine, human, mouse, rat
Anwendung
ELISA
western blot
Anti-CSF-1R/CD115 Antibody clone FER216, clone FER216, from mouse,
Speziesreaktivität
human
Anwendung
western blot
Anti-CSFR antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry
Anti-CSF-1R antibody, Rabbit monoclonal, clone SP211, recombinant, expressed in proprietary host, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Sunitinib malate, ≥98% (HPLC),
Spezies
human
Pazopanib, ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
FMS (539-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Csf1r,
Spezies
mouse
MISSION® esiRNA, targeting human CSF1R,
Spezies
human