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Merck

CHRM5

cholinergic receptor, muscarinic 5

Synonyme:
HM5
Spezies:
Human CHRM5 (1133), Mouse Chrm5 (213788), Rat Chrm5 (53949), naked mole-rat Chrm5 (101719201), Domestic Rabbit CHRM5 (100342984), dog CHRM5 (487472), Horse CHRM5 (100057856), cow CHRM5 (281686), sheep CHRM5 (101110766), domestic cat CHRM5 (101097246) ...Mehr
UniProtKB-ID:
P08912, Q96RG7
Gen-ID:
  • Human(1133) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]
  • Mouse(213788) cholinergic receptor, muscarinic 5
  • Rat(53949) cholinergic receptor, muscarinic 5
  • naked mole-rat(101719201) cholinergic receptor, muscarinic 5
  • Domestic Rabbit(100342984) cholinergic receptor, muscarinic 5
  • dog(487472) cholinergic receptor, muscarinic 5
  • Horse(100057856) cholinergic receptor, muscarinic 5
  • cow(281686) cholinergic receptor, muscarinic 5
  • sheep(101110766) cholinergic receptor, muscarinic 5
  • domestic cat(101097246) cholinergic receptor, muscarinic 5
  • chicken(428881) cholinergic receptor, muscarinic 5
  • domestic guinea pig(100379240) cholinergic receptor, muscarinic 5

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
P6503
Pilocarpin -hydrochlorid, ≥99% (titration), powder,
Spezies
human
A2251
Acetyl-β-Methylcholin-Chlorid, ≥98% (TLC), powder,
Spezies
human
P6628
Pilocarpin -nitrat (Salz), ≥98% (HPLC),
Spezies
human
O100
Oxotremorine M, solid,
Spezies
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
S1875
(−)-Scopolamin -hydrobromid Trihydrat, ≥98% (HPLC), powder,
Spezies
human
A0257
Atropin -sulfat (Salz) Monohydrat, ≥97% (TLC), crystalline,
Spezies
human
S8502
(−)-N-Methylhyosciniumbromid, ≥98% (HPLC), powder,
Spezies
human
S7882
(−)-Scopolamin-N-Butylbromid, ≥98% (TLC), powder,
Spezies
human
O2881
Oxybutyninchlorid, ≥98% (TLC), powder,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
HPA013172
Anti-CHRM5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
SAB4301748
Anti-CHRM5, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
SAB1405621
Anti-CHRM5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
A8404
Amitriptylin -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
D4526
Doxepin -hydrochlorid, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Spezies
human
51330
Harmalin, ≥95%,
Spezies
human, rat

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
A138
Aminobenztropine, solid,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
HTS075M
ChemiScreen Membrane Preparation
Recombinant Human M5 Muscarinic Acetylcholine Receptor, Human M5 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU130281
MISSION® esiRNA, targeting human CHRM5,
Spezies
human