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CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Synonyme:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

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ELISA

Produktnummer
Beschreibung
Spezies
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Pan-Cadherin antibody, Mouse monoclonal, clone CH-19, purified from hybridoma cell culture,
Speziesreaktivität
psammomys (sand rat), bovine, canine, cat, chicken, ferret, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, snake
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, serum, Upstate®,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-E-Cadherin antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP64, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat, clone DECMA-1, purified from hybridoma cell culture,
Speziesreaktivität
dog, mouse
Anwendung
immunofluorescence
immunoprecipitation (IP)

western blot

Cell Lines

Produktnummer
Beschreibung
Spezies
MCF10A CELLS CDH1 (-/-), ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Spezies
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Spezies
mouse

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Cdh1,
Spezies
mouse
MISSION® esiRNA, targeting human CDH1,
Spezies
human