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ATP1B1

ATPase, Na+/K+ transporting, beta 1 polypeptide

Synonyme:
ATP1B
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(481) Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
  • Mouse(11931) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Rat(25650) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • cow(519758) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Domestic Rabbit(100008749) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • Horse(100033968) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • naked mole-rat(101701102) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • chicken(396529) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • dog(403966) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • domestic cat(101081858) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • sheep(443384) ATPase, Na+/K+ transporting, beta 1 polypeptide
  • domestic guinea pig(100135483) ATPase, Na+/K+ transporting, beta 1 polypeptide

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ATP1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-ATP1B1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
dog, horse, human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-ATP1B1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
bovine, canine, human, mouse, pig, rat
Anwendung
ELISA
western blot
Anti-ATP1B1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Ouabain Octahydrat, ≥95% (HPLC), powder,
Spezies
rat, human
Digitoxin, ≥92% (HPLC), powder,
Spezies
human
Digoxin, analytical standard,
Spezies
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
Spezies

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Atp1b1,
Spezies
mouse
MISSION® esiRNA, targeting human ATP1B1,
Spezies
human