- Room-temperature Suzuki-Miyaura couplings in water facilitated by nonionic amphiphiles.
Room-temperature Suzuki-Miyaura couplings in water facilitated by nonionic amphiphiles.
Organic letters (2008-03-14)
Bruce H Lipshutz, Tue B Petersen, Alexander R Abela
PMID18335944
ABSTRACT
Use of a dilute aqueous solution containing a nonionic amphiphile allows efficient Suzuki-Miyaura cross-couplings of arylboronic acids with a wide array of aryl halides and pseudohalides, including sterically hindered and lipophilic substrates, in most cases at room temperature.
MATERIALS