- The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters.
The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters.
Chemical communications (Cambridge, England) (2012-07-13)
Apeng Liang, Xinjian Li, Dongfeng Liu, Jingya Li, Dapeng Zou, Yangjie Wu, Yusheng Wu
PMID22785428
ABSTRACT
The cross-coupling reactions of 1,1,1-trifluoro-2-iodoethane with aryl and heteroaryl boronic acid esters have been successfully achieved. The new protocol allows for a convenient introduction of trifluoroethyl groups into a variety of aryl and heteroaryl moieties under mild conditions.
MATERIALS