1460000

Neostigmine methyl sulfate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium methyl sulfate
• Empirical Formula (Hill Notation): C₁₃H₂₂N₂O₆S
• CAS Number: 51-60-5
• Molecular Weight: 334.39
• NACRES: NA.24
• PubChem Substance ID: 329750546
• UNSPSC Code: 41116107
• MDL number: MFCD00011796

Properties

• grade: pharmaceutical primary standard
• API family: neostigmine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: COS([O-])(=O)=O.CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
• InChI: 1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1
• InChI key: OSZNNLWOYWAHSS-UHFFFAOYSA-M
• Gene Information: human ... ACHE(43)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Neostigmine methyl sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Neostigmine Methylsulfate

Biochem/physiol Actions

Reversible inhibitor of acetylcholinesterase that is similar to eserine, but does not cross the blood-brain barrier.

Reversible inhibitor of acetylcholinesterase; does not cross the blood-brain barrier.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H300,H315,H319,H334,H335
• pcodes: P261 - P284 - P301 + P330 + P331 + P310 - P304 + P340 - P305 + P351 + P338 - P342 + P311
• Hazard Classifications: Acute Tox. 2 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable