SML3061
BSJ-04-122
>97% (HPLC)
Synonym(s):
N-(2-((5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)acrylamide
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About This Item
Empirical Formula (Hill Notation):
C15H12ClN5O
CAS Number:
Molecular Weight:
313.74
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
>97% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
BSJ-04-122 is a cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7) that binds to Cys247 of MKK4. It potently inhibits JNK phosphorylation. BSJ-04-122 exhibits antiproliferative effects against triple-negative breast cancer cells. Also, BSJ-04-122 enhances antiproliferative activity of JNK-IN-8.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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