M8569

Anti-MAFF (N-terminal) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): Anti-v-maf Avian Musculoaponeurotic Fibrosarcoma Oncogene Family, ProteinF
• MDL number: MFCD08705478
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 18 kDa
• species reactivity: human
• technique(s): immunoprecipitation (IP): 4-8 μL using A431 cell line; western blot: 1:4,000-1:8,000 using whole extracts of the A431 cell line
• UniProt accession no.: Q9ULX9
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MAFF(23764) ; mouse ... Maff(17133) ; rat ... Maff(366960)

Description

General description

Anti-MAFF (N-terminal) is developed in rabbit using a synthetic peptide corresponding to amino acids of human MAFF, conjugated to keyhole limpet hemocyanin (KLH) via a C-terminal added cysteine residue, as immunogen. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Human MAF bZIP transcription factor F (MAFF) encodes a 164 amino acids protein. It lacks an N-terminal transactivating domain.

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF) is a transcription factor which does not have a transactivation domain but possesses a leucine-zipper.

Immunogen

synthetic peptide corresponding to amino acids 2-17 of human MAFF, conjugated to KLH via a C-terminal added cysteine residue. The mouse and rat sequences differ from the human by one and two amino acids, respectively. Seven amino acids are identical in MaFG in the C-terminal region of the peptide.

Application

Anti-MAFF (N-terminal) antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.

Biochem/physiol Actions

The three small Maf proteins participates in development, differentiation, hematopoiesis and stress response.

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF) has been shown to interact with other transcription factors and it associates with certain regulatory sequences in the gene encoding the oxytocin receptor.

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.