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D122

Domperidone

≥98% (HPLC), Dopamine D2 receptor antagonist, powder

Synonym(s):

4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine

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Size/SKUAvailabilityPrice
25 mg
Please contact Customer Service for Availability
CZK 1,620.00
100 mg
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CZK 4,920.00
500 mg
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CZK 19,500.00

About This Item

Empirical Formula (Hill Notation):
C22H24ClN5O2
CAS Number:
Molecular Weight:
425.91
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
260-968-7
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

CZK 1,620.00


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Product Name

Domperidone, powder, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: >10 mg/mL, 0.1 M HCl: soluble, 0.1 M NaOH: slightly soluble, H2O: insoluble

originator

Johnson & Johnson

SMILES string

Clc1ccc2N(C3CCN(CCCN4C(=O)Nc5ccccc45)CC3)C(=O)Nc2c1

InChI

1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)

InChI key

FGXWKSZFVQUSTL-UHFFFAOYSA-N

Biochem/physiol Actions

Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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1 of 1

This Item
H3041D129E101
form

powder

form

powder

form

solid

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

DMSO: >10 mg/mL, 0.1 M NaOH: slightly soluble, H2O: insoluble, 0.1 M HCl: soluble

solubility

DMSO: >10 mg/mL

solubility

H2O: insoluble <0.11 mg/mL, DMSO: >20 mg/mL, 0.1 M HCl: insoluble, 0.1 M NaOH: soluble, ethanol: soluble

solubility

H2O: soluble >10 mg/mL, ethanol: soluble 2.6 mg/mL, 0.1 M HCl: soluble 7 mg/mL

color

white

color

off-white

color

white

color

off-white

Gene Information

human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), KCNH2(3757)
rat ... Drd1a(24316), Drd2(24318), Drd3(29238), Htr3a(79246)

Gene Information

-

Gene Information

-

Gene Information

human ... DRD2(1813)


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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