707031

6-Methoxy-2-(tributylstannyl)pyrimidine

95%

• Empirical Formula (Hill Notation): C₁₇H₃₂N₂OSn
• CAS Number: 850501-35-8
• Molecular Weight: 399.16
• MDL number: MFCD15143643
• UNSPSC Code: 12352103
• PubChem Substance ID: 329762684
• NACRES: NA.22

Properties

• Assay: 95%
• form: liquid
• refractive index: n20/D 1.507
• bp: 293 °C
• density: 1.164 g/mL at 25 °C
• SMILES string: CCCC[Sn](CCCC)(CCCC)c1nccc(OC)n1
• InChI: 1S/C5H5N2O.3C4H9.Sn/c1-8-5-2-3-6-4-7-5;3*1-3-4-2;/h2-3H,1H3;3*1,3-4H2,2H3;
• InChI key: HQUSEOSQVFRYQV-UHFFFAOYSA-N

Description

General description

6-Methoxy-2-(tributylstannyl)pyrimidine is an organotin compound used in Stille coupling reaction.

Application

6-Methoxy-2-(tributylstannyl)pyrimidine can be used as a reactant for the preparation of substituted pyrimidinone compounds via a Stille coupling reaction with aryl bromides. It can be also employed for the preparation of 4-methoxy-2-phenylpyrimidine by reacting with iodobenzene using Pd as a catalyst.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301,H312,H315,H319,H360FD,H372,H410
• Precautionary Statements: P202 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves