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Merck

RASD1

RAS, dexamethasone-induced 1

Synonyms:
AGS1, DEXRAS1, MGC:26290
Species:
UniProtKB ID:
Gene ID:
  • Human(51655) Summary: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011]
  • Mouse(19416) RAS, dexamethasone-induced 1
  • Rat(64455) RAS, dexamethasone-induced 1
  • chicken(416507) RAS, dexamethasone-induced 1
  • Zebrafish(393504) RAS, dexamethasone-induced 1
  • naked mole-rat(101707211) RAS, dexamethasone-induced 1
  • dog(489542) RAS, dexamethasone-induced 1
  • sheep(100302075) RAS, dexamethasone-induced 1
  • domestic cat(101080588) RAS, dexamethasone-induced 1
  • cow(507449) RAS, dexamethasone-induced 1
  • domestic guinea pig(100730809) RAS, dexamethasone-induced 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RASD1 antibody produced in mouse, clone 2D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
Anti-RASD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Dexras1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-DEXRAS1 Antibody, clone 4B11.1, clone 4B11.1, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-B-Raf Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RASD1,
Species
human