PLAT
plasminogen activator, tissue
Synonyms:
T-PA, TPA
Species:
Human PLAT (5327), Mouse Plat (18791), Rat Plat (25692), naked mole-rat Plat (101713266), domestic guinea pig Plat (100725281), cow PLAT (281407), sheep PLAT (101118332), chicken PLAT (426791), domestic cat PLAT (101100299), Horse PLAT (100050239) ...More
UniProtKB ID:
Gene ID:
- Human(5327) Summary: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(18791) plasminogen activator, tissue
- Rat(25692) plasminogen activator, tissue
- naked mole-rat(101713266) plasminogen activator, tissue
- domestic guinea pig(100725281) plasminogen activator, tissue
- cow(281407) plasminogen activator, tissue
- sheep(101118332) plasminogen activator, tissue
- chicken(426791) plasminogen activator, tissue
- domestic cat(101100299) plasminogen activator, tissue
- Horse(100050239) plasminogen activator, tissue
- dog(482840) plasminogen activator, tissue
- Zebrafish(100320028) plasminogen activator, tissue
- Domestic Rabbit(100009556) plasminogen activator, tissue
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PLAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PLAT antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Tissue Plasminogen Activator (Ab-1) Mouse mAb (GMA-043), liquid, clone GMA-043, Calbiochem®,
Species Reactivity
human
Application
Anti-tPA/PLAT antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
ANTI-TPA (CENTER) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Aminocaproic acid, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Proteins
Product Number
Description
Species