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Merck

PADI3

peptidyl arginine deiminase, type III

Synonyms:
PAD3, PDI3
Species:
UniProtKB ID:
Gene ID:
  • Human(51702) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
  • Mouse(18601) peptidyl arginine deiminase, type III
  • Rat(29520) peptidyl arginine deiminase, type III
  • naked mole-rat(101722435) peptidyl arginine deiminase, type III
  • chicken(395910) peptidyl arginine deiminase, type III
  • dog(478216) peptidyl arginine deiminase, type III
  • Horse(100049897) peptidyl arginine deiminase, type III
  • domestic cat(101085813) peptidyl arginine deiminase, type III
  • cow(508160) peptidyl arginine deiminase, type III
  • sheep(443369) peptidyl arginine deiminase, type III
  • Domestic Rabbit(100350962) peptidyl arginine deiminase, type III
  • domestic guinea pig(100727956) peptidyl arginine deiminase, type III

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PADI3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PADI3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
PADI-3 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE),
Species
human
PAD Cocktail, Active, recombinant,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Padi3,
Species
mouse
MISSION® esiRNA, targeting human PADI3,
Species
human