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Merck

ITPR1

inositol 1,4,5-trisphosphate receptor, type 1

Synonyms:
INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29
Species:
UniProtKB ID:
Gene ID:
  • Human(3708) Summary: This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
  • Mouse(16438) inositol 1,4,5-trisphosphate receptor 1
  • Rat(25262) inositol 1,4,5-trisphosphate receptor, type 1
  • cow(317697) inositol 1,4,5-trisphosphate receptor, type 1
  • Zebrafish(100149388) inositol 1,4,5-triphosphate receptor, type 1
  • domestic guinea pig(100713023) inositol 1,4,5-trisphosphate receptor, type 1
  • dog(476548) inositol 1,4,5-trisphosphate receptor, type 1
  • Horse(100052808) inositol 1,4,5-trisphosphate receptor, type 1
  • sheep(101108864) inositol 1,4,5-trisphosphate receptor, type 1
  • sheep(100500722) inositol 1,4,5-trisphosphate receptor, type 1
  • chicken(395412) inositol 1,4,5-trisphosphate receptor, type 1
  • naked mole-rat(101706047) inositol 1,4,5-trisphosphate receptor, type 1
  • domestic cat(101100546) inositol 1,4,5-trisphosphate receptor, type 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IP3 Receptor 1 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Monoclonal Anti-ITPR1 antibody produced in mouse, clone S24-18, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-ITPR1 antibody produced in mouse, clone 2B6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-IP3 Receptor Antibody, from rabbit,
Species Reactivity
bovine, canine, dog, human, mouse, pig, rabbit, rat
Application
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot
Anti-InsP3R Antibody, Type 1, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, pig, porcine, primate, rat, rhesus macaque
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ITPR1,
Species
human
MISSION® esiRNA, targeting mouse Itpr1,
Species
mouse