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Merck

HIST2H4B

histone cluster 2, H4b

Synonyms:
H4/o
Species:
Human HIST2H4B (554313)
UniProtKB ID:
Gene ID:
  • Human(554313) Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Jul 2008]

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Antibodies

Product Number
Description
Species Reactivity
Application
07-213-I
Anti-dimethyl-Histone H4 (Arg3) Asymmetric Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
dot blot
immunoprecipitation (IP)
western blot
07-595
Anti-acetyl-Histone H4 (Lys12) Antibody, serum, Upstate®,
Species Reactivity
saccharomyces cerevisiae, human
Application
ChIP
dot blot
western blot
07-596
Anti-Histone H4 (citrulline 3) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
ChIP
immunocytochemistry
immunohistochemistry
western blot
07-748-AF647
Anti-monomethyl Histone H4 (Lys20) Antibody, Alexa Fluor™ 647 Conjugate, 0.5 mg/mL, from rabbit,
Species Reactivity
human
Application
immunocytochemistry
ABE441
Anti-dimethyl Histone H4 (Arg3), Asymmetric Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
dot blot
immunocytochemistry
western blot