Skip to Content
Merck

CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

Synonyms:
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Species:
UniProtKB ID:
Gene ID:
  • Human(1140) Summary: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(11443) cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
  • Rat(24261) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic cat(101097433) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Domestic Rabbit(100357163) cholinergic receptor, nicotinic, beta 1 (muscle)
  • sheep(101121614) cholinergic receptor, nicotinic, beta 1 (muscle)
  • naked mole-rat(101723288) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic guinea pig(100714100) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Zebrafish(100006941) cholinergic receptor, nicotinic, beta 1 (muscle)
  • dog(489473) cholinergic receptor, nicotinic, beta 1 (muscle)
  • cow(282179) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Horse(100072990) cholinergic receptor, nicotinic, beta 1 (muscle)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
Decamethonium bromide, Ion-Pair reagent, ≥99%,
Species
human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat
Decamethonium bromide, crystalline,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
Pancuronium bromide, ,
Species
human
Tubocurarine hydrochloride pentahydrate, ≥97%,
Species
human
Vecuronium bromide, ,
Species
human
Pancuronium bromide, European Pharmacopoeia (EP) Reference Standard,
Species
human
Vecuronium bromide, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Blocker

Product Number
Description
Species
Hexamethonium chloride, solid (hygroscopic),
Species
human
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Hexamethonium bromide, ,
Species
human
Kynurenic acid, ≥98%,
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Chrnb1,
Species
mouse
MISSION® esiRNA, targeting human CHRNB1,
Species
human