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Merck

CCR8

chemokine (C-C motif) receptor 8

Synonyms:
CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1
Species:
UniProtKB ID:
Gene ID:
  • Human(1237) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
  • Mouse(12776) chemokine (C-C motif) receptor 8
  • Rat(301066) chemokine (C-C motif) receptor 8
  • domestic guinea pig(100725278) chemokine (C-C motif) receptor 8
  • naked mole-rat(101706054) chemokine (C-C motif) receptor 8
  • domestic cat(101099650) chemokine (C-C motif) receptor 8
  • cow(407772) chemokine (C-C motif) receptor 8
  • sheep(101113281) chemokine (C-C motif) receptor 8
  • dog(485600) chemokine (C-C motif) receptor 8
  • chicken(420718) chemokine (C-C motif) receptor 8

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CCR8 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-CCR8 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-CCR8 Antibody, clone 9N1Y1, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
western blot
Anti-CCR8 Antibody, clone C8Mab-2, ,
Species Reactivity
mouse
Application
flow cytometry
immunocytochemistry
Anti-CCR8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CCR8,
Species
human
MISSION® esiRNA, targeting mouse Ccr8,
Species
mouse