BAG4
BCL2-associated athanogene 4
Synonyms:
BAG-4, SODD
Species:
Human BAG4 (9530), Mouse Bag4 (67384), Rat Bag4 (361167), domestic cat BAG4 (101087659), dog BAG4 (607954), chicken BAG4 (426776), Zebrafish bag4 (100001980), Thale Cress BAG4 (824341), domestic guinea pig Bag4 (100731898), naked mole-rat Bag4 (101707505) ...More
UniProtKB ID:
Gene ID:
- Human(9530) Summary: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
- Mouse(67384) BCL2-associated athanogene 4
- Rat(361167) BCL2-associated athanogene 4
- domestic cat(101087659) BCL2-associated athanogene 4
- dog(607954) BCL2-associated athanogene 4
- chicken(426776) BCL2-associated athanogene 4
- Zebrafish(100001980) BCL2-associated athanogene 4
- Thale Cress(824341) BCL-2-associated athanogene 4
- domestic guinea pig(100731898) BCL2-associated athanogene 4
- naked mole-rat(101707505) BCL2-associated athanogene 4
- sheep(101118503) BCL2-associated athanogene 4
- Horse(100057730) BCL2-associated athanogene 4
- cow(516353) BCL2-associated athanogene 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SODD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-BAG4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-BAG4 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-BAG4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-BAG4 antibody produced in mouse, clone 2G9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot