Přejít k obsahu
Merck

Solubilization of active opiate receptors.

Proceedings of the National Academy of Sciences of the United States of America (1980-08-01)
W F Simonds, G Koski, R A Streaty, L M Hjelmeland, W A Klee
ANOTACE

Receptors that reversibly bind opiates and opioid peptides have been solubilized from brain and neuroblastoma-glioma hybrid cell NG108-15 membranes. Active receptors are specifically solubilized with a new type of detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, which is a zwitterionic derivative of cholic acid. The solubilized receptor complexes behave as large molecules with a Stokes radius of 70 A and contain protein as an essential constituent.

MATERIÁLY
Číslo produktu
Značka
Popis produktu

Sigma-Aldrich
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate, 98%
Avanti
CHAPSO, Avanti Research - A Croda Brand 850501P, powder