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1279804

USP

Fluoxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyma:

(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac®

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About This Item

Empirický vzorec (Hillův zápis):
C17H18F3NO · HCl
Číslo CAS:
56296-78-7
Molekulová hmotnost:
345.79
MDL number:
MFCD00214288
UNSPSC Code:
41116107
PubChem Substance ID:
329749876
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

fluoxetine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

Inchi Key

GIYXAJPCNFJEHY-UHFFFAOYSA-N

Gene Information

human ... SLC6A4(6532)

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Související kategorie

Application

Fluoxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Fluoxetine Tablets
  • Fluoxetine Delayed-Release Capsules
  • Olanzapine and Fluoxetine Capsules
  • Fluoxetine Oral Solution
  • Fluoxetine Capsules

Biochem/physiol Actions

Selective serotonin reuptake inhibitor; antidepressant.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Legal Information

Sold under license from Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.

related product

Č. produktu
Popis
Stanovení ceny

F0253030

Fluoxetine impurity C, European Pharmacopoeia (EP) Reference Standard

1279826

Fluoxetine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1279837

Fluoxetine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1279815

Fluoxetine Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP797

Fluoxetine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR1953

Fluoxetine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1952

Fluoxetine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2041

Fluoxetine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002201

Fluoxetine impurity A, CRS, European Pharmacopoeia (EP) Reference Standard

Y0002219

Fluoxetine hydrochloride for ID and assay, CRS, European Pharmacopoeia (EP) Reference Standard

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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1500218

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Isoniazid United States Pharmacopeia (USP) Reference Standard

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1349706

Isoniazid

Ketanserin (+)-tartrate salt ≥97%, solid

Sigma-Aldrich

S006

Ketanserin (+)-tartrate salt

Citalopram hydrobromide ≥98% (HPLC)

Sigma-Aldrich

C7861

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Arachidonylethanolamide ≥97.0% (TLC), oil

Sigma-Aldrich

A0580

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Sertraline hydrochloride ≥98% (HPLC)

Sigma-Aldrich

S6319

Sertraline hydrochloride

R J Gonzalez-Rothi et al.
Chest, 107(6), 1763-1765 (1995-06-01)
We describe a patient who developed progressive dyspnea, lung infiltrates, and restrictive lung disease in association with the antidepressant fluoxetine hydrochloride (Prozac). The pathologic findings were consistent with hypersensitivity pneumonitis. An associated pulmonary phospholipidosis was also noted.
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we
Sean C Godar et al.
Journal of psychiatric research, 56, 1-9 (2014-06-03)
The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its degradation by monoamine oxidase (MAO)-A. MAO-A deficiency results in a wide set of behavioral alterations, including perseverative behaviors and
Kristie T Ota et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(3), 711-718 (2014-09-03)
Major depressive disorder (MDD) is a debilitating and widespread illness that exerts significant personal and socioeconomic consequences. Recent genetic and brain-imaging studies suggest that bicaudal C homolog 1 gene (BICC1), which codes for an RNA-binding protein, may be associated with
Rody Kingston et al.
PLoS genetics, 17(11), e1009885-e1009885 (2021-11-05)
Molecular insights into the selective vulnerability of retinal ganglion cells (RGCs) in optic neuropathies and after ocular trauma can lead to the development of novel therapeutic strategies aimed at preserving RGCs. However, little is known about what molecular contexts determine
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