1164700

Daunorubicin hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonyma: Daunorubicin hydrochloride, Daunomycin hydrochloride
• Empirický vzorec (Hillův zápis): C₂₇H₂₉NO₁₀ · HCl
• Číslo CAS: 23541-50-6
• Molekulová hmotnost: 563.98
• Beilstein/REAXYS Number: 4229221
• MDL number: MFCD04974507
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749523
• NACRES: NA.24

Vlastnosti

• grade: pharmaceutical primary standard
• API family: daunorubicin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
• InChI: 1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22+,27-;/m0./s1
• InChI key: GUGHGUXZJWAIAS-QQYBVWGSSA-N
• Gene Information: human ... TOP2A(7153)

Popis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Daunorubicin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Daunorubicin Hydrochloride for Injection
• Doxorubicin Hydrochloride

Biochem/physiol Actions

Potent anticancer agent. Inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H341,H351,H360FD
• pcodes: P201 - P202 - P264 - P270 - P280 - P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 2 - Muta. 2 - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3