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Hlavní dokumenty

1075305

USP

Bisdesmethoxycurcumin

United States Pharmacopeia (USP) Reference Standard

Synonyma:

1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

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About This Item

Empirický vzorec (Hillův zápis):
C19H16O4
Číslo CAS:
Molekulová hmotnost:
308.33
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

curcumin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)O

InChI

1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+

InChI key

PREBVFJICNPEKM-YDWXAUTNSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bisdesmethoxycurcumin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Curcuminoids
  • Curcuminoids Capsules
  • Curcuminoids Tablets
  • Powdered Turmeric
  • Powdered Turmeric Extract
  • Turmeric

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Osvědčení o analýze (COA)

Lot/Batch Number

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Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin)

Sigma-Aldrich

C7727

Curcumin

Curcumin from Curcuma longa (Turmeric), powder

Sigma-Aldrich

C1386

Curcumin

Curcumin primary reference standard

00280590

Curcumin

Sudha Ponnusamy et al.
Food chemistry, 135(4), 2638-2642 (2012-09-18)
Curcuma longa rhizome is used extensively in culinary preparations in Far East and South-East Asia. Health benefits of curcuminoids from C. longa as antioxidants, anti-cancer and anti-inflammatory molecules have been well documented. We report here for the first time that
Dong-Chan Kim et al.
BMB reports, 45(4), 221-226 (2012-04-26)
Curcumin, a polyphenol responsible for the yellow color of the curry spice turmeric, possesses antiinflammatory, antiproliferative and antiangiogenic activities. However, anticoagulant activities of curcumin have not been studied. Here, the anticoagulant properties of curcumin and its derivative (bisdemethoxycurcumin, BDMC) were
J R Cashman et al.
Neuro-degenerative diseases, 10(1-4), 274-276 (2011-12-14)
Neurodegenerative diseases are associated with accumulation of modified proteins or peptides including amyloid-β (Aβ) in Alzheimer's disease (AD), and misfolded superoxide dismutase-1 (SOD-1) in amyotrophic lateral sclerosis (ALS). Clearance of Aβ or SOD-1 by the innate immune system may be
Y-L Liu et al.
Current cancer drug targets, 11(9), 1098-1110 (2011-09-22)
Hypermethylation of the Wnt inhibitory factor-1 (WIF-1) promoter has been implicated in the overactivation of the Wnt pathway in human lung cancer. Curcuminoids exert anti-cancer effects and have been reported to act as hypomethylating agents. Previously, we have investigated and
Hironobu Ozawa et al.
Ambio, 41 Suppl 2, 149-150 (2012-06-13)
The first example of a ruthenium sensitizer (TUS-22) having a natural dye, bisdemethoxycurcumin, as a ligand has been synthesized. The dye-sensitized solar cell based on this novel dye showed 5.8% conversion efficiency under AM 1.5 (100 mW/cm(2)) irradiation.

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