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Merck

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T4069

JC-1

≥97% purity, solid

Synonyma:

5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolocarbocyanine iodide, CBIC2(3)

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Velikost baleníSkladová položkaDostupnostCena
5 mg
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
29 000,00 Kč

O této položce

Empirický vzorec (Hillův zápis):
C25H27Cl4IN4
Číslo CAS:
Molekulová hmotnost:
652.23
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
MDL number:

29 000,00 Kč


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Název produktu

JC-1, powder or solid (Crystals)

assay

≥97%

Quality Segment

form

powder or solid (Crystals)

technique(s)

titration: suitable

color

faint red to very dark red

ε (extinction coefficient)

≥175000 at 511-517 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[I-].CCN1C(=C\C=C\c2n(CC)c3cc(Cl)c(Cl)cc3[n+]2CC)/N(CC)c4cc(Cl)c(Cl)cc14

InChI

1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1

InChI key

FYNNIUVBDKICAX-UHFFFAOYSA-M

Application

The cyanine dye JC-1 has been used to determine mitochondrial transmembrane potential.
A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent (λex 520 nm) monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent (λem 596 nm ) "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.

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Tato položka
SML3593PHL8916650636
JC-1 powder or solid (Crystals)

Sigma-Aldrich

T4069

JC-1

I3,II8-Biapigenin phyproof® Reference Substance

PHL89166

I3,II8-Biapigenin

technique(s)

titration: suitable

technique(s)

-

technique(s)

-

technique(s)

-

color

faint red to very dark red

color

white to beige

color

-

color

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

-

application(s)

agriculture

form

powder or solid (Crystals)

form

powder

form

solid

form

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

assay

≥97%

assay

≥95% (HPLC)

assay

≥98.0% (HPLC)

assay

≥98.0% (HPLC)


Skladovací třída

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Osvědčení o analýze (COA)

Lot/Batch Number

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Globální číslo obchodní položky

Skladová položkaGTIN
T4069-5MG04061837345500

Questions

  1. Mitochondria Staining Kit (CS0390)에 들어있는 1MG-JC-1 powder와 다른 제품인가요? 동일 농도로 DMSO이용해 녹였더니 Stock 색상이 다릅니다.

    1 answer
    1. Yes, the T4069, JC-1 product is also supplied in the Mitochndria Stain kit, CS0390. Both are prepared at 1 mg/mL in DMSO resulting in a red solution. Slight variations in color may be considered normal and the result of lot-to-lot variability. Marked differences in color should be discussed with Technical Service.

      Should this be the case, please navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquiries" under the Products Section and respond with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.

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