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SML2517

Tanshinone II-A sodium sulfonate

≥95%

Synonym(s):

6,7,8,9,10,11-hexahydro-1,6,6-Trimethyl-10,11-dioxo-phenanthro[1,2-b]furan-2-sulfonic acid sodium salt, Sodium tanshinone IIA sulfonate, Sulfotanshinone sodium II-A, TIIAS

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Size/SKUAvailabilityPrice
10 mg
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$69.60

About This Item

Empirical Formula (Hill Notation):
C19H17NaO6S
CAS Number:
Molecular Weight:
396.39
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95%
Form:
powder

$69.60


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assay

≥95%

form

powder

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CC1(C)CCCC2=C3C(C(OC(S(=O)(O[Na])=O)=C4C)=C4C(C3=O)=O)=CC=C21

InChI

1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1

InChI key

AZEZEAABTDXEHR-UHFFFAOYSA-M

Biochem/physiol Actions

Tanshinone II A sulfonate is a water-soluble derivative of tanshinone II A that exhibits anti-inflammatory properties in rodent models of hepatitis and sepsis. Tanshinone II A sulfonate targets Ca2+-activated potassium channels and carboxylesterase 2. Recent studies indicate that tanshinone II A sulfonate but not tanshinone II A acts as potent negative allosteric modulator of the human purinergic receptor P2X7.
anti-inflammatory, potent negative allosteric modulator of the human purinergic receptor P2X7

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This Item
T4952SML2148C5624
form

powder

form

powder

form

powder

form

powder

assay

≥95%

assay

≥97% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

H2O: 2 mg/mL, clear (warmed)

solubility

methanol: 5 mg/mL, clear, red-orange to red

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: ≥5 mg/mL

color

white to beige

color

orange to dark red

color

white to beige

color

orange-brown


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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