S9666

Sphingosine 1-phosphate

≥95% (TLC), powder, lipid second messenger

• Synonyma: (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-phosphate, D-erythro-Sphingosine 1-phosphate
• Empirický vzorec (Hillův zápis): C₁₈H₃₈NO₅P
• Číslo CAS: 26993-30-6
• Molekulová hmotnost: 379.47
• MDL number: MFCD00270077
• UNSPSC Code: 12352211
• PubChem Substance ID: 24899853
• NACRES: NA.77

Vlastnosti

• product name: Sphingosine 1-phosphate, ≥95%, powder
• Quality Level: 300
• assay: ≥95%
• form: powder
• storage temp.: −20°C
• SMILES string: CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O
• InChI: 1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
• InChI key: DUYSYHSSBDVJSM-KRWOKUGFSA-N
• Gene Information: human ... S1PR1(1901) , S1PR2(9294) , S1PR3(1903) , S1PR4(8698) , S1PR5(53637)

Popis

Biochem/physiol Actions

A lipid second messenger that binds to S1P₁ and S1P₃ receptors. Mobilizes intracellular Ca²⁺ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis.

Features and Benefits

This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves