S7446
Superoxide Dismutase from bovine erythrocytes
BioUltra, lyophilized powder, ≥4,500 units/mg protein, ≥97% (SDS-PAGE)
Synonym(s):
SOD, Superoxide: superoxide oxidoreductase
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| Size/SKU | Availability | Price |
|---|---|---|
15000 units | Check Cart for Availability | $247.00 |
75000 units | Check Cart for Availability | $1,030.00 |
About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-943-0
MDL number:
Specific activity:
≥4,500 units/mg protein
Assay:
≥97% (SDS-PAGE)
product line
BioUltra
Quality Segment
assay
≥97% (SDS-PAGE)
form
lyophilized powder
specific activity
≥4,500 units/mg protein
mol wt
32.5 kDa
composition
Protein, ≥95% biuret
relevant disease(s)
arthritis
storage temp.
−20°C
General description
Research area: Cell signaling. Superoxide Dismutase (SOD) is found in allaerobic cells of the animals, plants, and microorganisms. It is a low molecularweight protein that exists as three different forms such as manganese SOD,copper–zinc SOD, and extracellular SOD.[1]
Application
Superoxide Dismutase from bovine erythrocytes has been used in a study to assess activity parameters in adjuvant-induced arthritis. [2] Superoxide Dismutase from bovine erythrocytes has also been used in a study to simplify the process of purifying superoxide dismutases using charge-controlled hydrophobic chromatography on 10-carboxydecyl Sepharose. It has also been used as a standard in SOD assay in mice liver andkidney samples.
Biochem/physiol Actions
Superoxide Dismutase from bovine erythrocytes catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. It serves as an antioxidant and plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice.
Other Notes
One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 °C in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.
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This Item | |||
|---|---|---|---|
| specific activity ≥4,500 units/mg protein | specific activity ≥3,000 units/mg protein | specific activity ≥2500 units/mg protein | specific activity ≥3000 units/mg dry wt. |
| assay ≥97% (SDS-PAGE) | assay - | assay ≥90% (SDS-PAGE) | assay - |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form lyophilized solid |
| mol wt 32.5 kDa | mol wt 32.5 kDa | mol wt - | mol wt - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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