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Key Documents

P7127

Sigma-Aldrich

Phospho(enol)pyruvic acid monopotassium salt

≥97% (enzymatic), powder

Synonyma:

2-(Phosphonooxy)-2-propenoic acid monopotassium salt, mono-Potassium phosphoenolpyruvate, PEP-K

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Empirický vzorec (Hillův zápis):
C3H4KO6P
Číslo CAS:
Molekulová hmotnost:
206.13
Beilstein/REAXYS Number:
4603446
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

Phospho(enol)pyruvic acid monopotassium salt, ≥97% (enzymatic)

Quality Level

assay

≥97% (enzymatic)

form

powder

solubility

water: 100 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[K+].OC(=O)C(=C)OP(O)([O-])=O

InChI

1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1

InChI key

SOSDSEAIODNVPX-UHFFFAOYSA-M

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General description

Phospho(enol)pyruvic acid (PEP) acts as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase. It is a bifunctional carbohydrate, which exhibits antioxidant property. PEP may be a potential organ preservation agent in clinical transplantation.

Application

Phospho(enol)pyruvic acid monopotassium salt has been used:
  • to maintain a constant concentration of adenosine triphosphate (ATP) for active gel assembly
  • as a component in assay buffer for in vitro ATPase assay
  • as a stock solution for optical trapping assay

Biochem/physiol Actions

Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Osvědčení o analýze (COA)

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Phosphoenolpyruvic acid, an intermediate of glycolysis, attenuates cellular injury induced by hydrogen peroxide and 2-deoxy-D-glucose in the porcine proximal kidney tubular cell line, LLC-PK1
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Journal of Health Science, 56(6), 727-732 (2010)
W J Bettger et al.
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